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Lars Larsson Selected Research

Myosins (Myosin)

1/2022Electrical stimulated GLUT4 signalling attenuates critical illness-associated muscle wasting.
1/2022Acute and severe trabecular bone loss in a rat model of critical illness myopathy.
11/2020Neurogenic vs. Myogenic Origin of Acquired Muscle Paralysis in Intensive Care Unit (ICU) Patients: Evaluation of Different Diagnostic Methods.
8/2016Impaired Ca(2+) release contributes to muscle weakness in a rat model of critical illness myopathy.
1/2016Mechanical Signaling in the Pathophysiology of Critical Illness Myopathy.
1/2016Mechano-signalling pathways in an experimental intensive critical illness myopathy model.
5/2014The Effect of Nutritional Status in the Pathogenesis of Critical Illness Myopathy (CIM).
1/2014Masseter muscle myofibrillar protein synthesis and degradation in an experimental critical illness myopathy model.
6/2013Impaired autophagy, chaperone expression, and protein synthesis in response to critical illness interventions in porcine skeletal muscle.
11/2012Loss of muscle strength during sepsis is in part regulated by glucocorticoids and is associated with reduced muscle fiber stiffness.
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Lars Larsson Research Topics

Disease

28Critical Illness (Critically Ill)
01/2022 - 09/2007
22Muscular Diseases (Myopathy)
01/2022 - 04/2008
13Muscle Weakness
01/2022 - 06/2007
9Sepsis (Septicemia)
06/2013 - 01/2008
6Muscular Atrophy (Muscle Atrophy)
01/2019 - 09/2007
5Paralysis (Palsy)
01/2022 - 01/2011
4Atrophy
01/2022 - 05/2014
4Neoplasms (Cancer)
01/2021 - 12/2003
3COVID-19
01/2022 - 01/2020
2Inflammation (Inflammations)
01/2021 - 01/2021
2Cachexia
01/2021 - 04/2008
2Asthma (Bronchial Asthma)
09/2018 - 12/2002
2Charcot-Marie-Tooth Disease (Peroneal Muscular Atrophy)
08/2014 - 09/2008
2Allergic Rhinitis
04/2007 - 02/2006
1Paresis (Hemiparesis)
01/2022
1Virus Diseases (Viral Diseases)
01/2021
1Cytokine Release Syndrome
01/2021
1Polyneuropathies (Polyneuropathy)
11/2020
1Quadriplegia (Spastic Quadriplegia)
11/2020
1Hemorrhage
11/2020
1Heart Diseases (Heart Disease)
08/2015
1Dilated Cardiomyopathy (Cardiomyopathy, Congestive)
08/2015
1Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
08/2014
1Hypertrophy
10/2013
1Disease Progression
06/2013
1Arthrogryposis
05/2010
1Hyperglycemia
02/2010
1Wasting Syndrome (Wasting Disease)
02/2010
1Myofibrillar Myopathy
01/2009
1Demyelinating Diseases (Demyelinating Disease)
09/2008
1Nervous System Diseases (Neurological Disorders)
09/2008
1Congenital Hypothyroidism (Cretinism)
02/2008
1Congenital Abnormalities (Deformity)
06/2007

Drug/Important Bio-Agent (IBA)

17Myosins (Myosin)IBA
01/2022 - 06/2007
16Proteins (Proteins, Gene)FDA Link
01/2022 - 06/2002
8Adrenal Cortex Hormones (Corticosteroids)IBA
06/2013 - 01/2008
4Hormones (Hormone)IBA
01/2021 - 01/2008
4Neuromuscular Blocking AgentsIBA
06/2013 - 01/2011
3Biomarkers (Surrogate Marker)IBA
01/2017 - 07/2004
3Protein Isoforms (Isoforms)IBA
08/2015 - 02/2008
3EndotoxinsIBA
09/2012 - 01/2011
3TropomyosinIBA
05/2010 - 06/2007
2Thyroid HormonesIBA
01/2021 - 01/2021
2EnzymesIBA
11/2020 - 12/2003
2Contractile ProteinsIBA
12/2016 - 01/2016
2Phosphotransferases (Kinase)IBA
04/2013 - 09/2012
2Heat-Shock Proteins (Heat-Shock Protein)IBA
04/2013 - 09/2012
2GlucocorticoidsIBA
11/2012 - 12/2002
2Glucose (Dextrose)FDA LinkGeneric
05/2012 - 02/2010
2Insulin (Novolin)FDA Link
01/2012 - 02/2010
2Messenger RNA (mRNA)IBA
01/2012 - 02/2010
2Histamine Antagonists (Antihistamines)IBA
04/2007 - 02/2006
1MineralsIBA
01/2022
1Activating Transcription Factor 4IBA
01/2022
1Bone Morphogenetic Proteins (Bone Morphogenetic Protein)IBA
01/2021
1Therapeutic UsesIBA
01/2021
1Complement C3 (C3 Complement)IBA
01/2021
1activin AIBA
01/2021
1Interleukin-6 (Interleukin 6)IBA
01/2021
1AnticoagulantsIBA
11/2020
1Propofol (Diprivan)FDA LinkGeneric
01/2020
1VBP15 compoundIBA
01/2019
1Ligases (Synthetase)IBA
01/2019
1RNA (Ribonucleic Acid)IBA
01/2019
1prednylidene (Pred)IBA
01/2019
1CalpainIBA
01/2019
1Nitric Oxide (Nitrogen Monoxide)FDA Link
09/2018
1PowdersIBA
09/2018
1Immunoglobulin FragmentsIBA
09/2018
1AntigensIBA
09/2018
1Interleukin-13IBA
09/2018
1Monoclonal AntibodiesIBA
09/2018
1BGP 15IBA
01/2016
1ProteomeIBA
08/2014
1Bone Morphogenetic Protein ReceptorsIBA
10/2013
1Glucocorticoid Receptors (Glucocorticoid Receptor)IBA
11/2012
1Mifepristone (RU 486)FDA Link
11/2012
1Dexamethasone (Maxidex)FDA LinkGeneric
11/2012
1ChemokinesIBA
09/2012
1Amino AcidsFDA Link
05/2012
1LipidsIBA
05/2012
1Peptide Hydrolases (Proteases)FDA Link
01/2012
1nebulinIBA
06/2011
1salicylhydroxamic acid (SHAM)IBA
01/2011
1UbiquitinIBA
02/2010
1Cathepsin LIBA
02/2010
1Proteasome Endopeptidase Complex (Proteasome)IBA
02/2010
1Trinitrotoluene (TNT)IBA
09/2008
1Troponin T (Troponin T1)IBA
09/2008
1Transcription Factors (Transcription Factor)IBA
09/2007

Therapy/Procedure

11Artificial Respiration (Mechanical Ventilation)
01/2022 - 01/2008
10Critical Care (Surgical Intensive Care)
01/2022 - 09/2007
10Mechanical Ventilators (Ventilator)
01/2022 - 09/2007
3Parenteral Nutrition
01/2022 - 02/2010
3Denervation
01/2021 - 01/2012
2Therapeutics
11/2020 - 01/2012
1Muscle Denervation
08/2014
1Ligation
11/2012
1Punctures
11/2012
1Length of Stay
09/2007